Thermo Fisher Scientific WASP Polyclonal Antibody
WASP 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 시료 반응. Protein A로 정제된 1 mg/mL 액상 제품으로, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human WASP (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structures and are involved in transducing signals from cell surface receptors to the actin cytoskeleton. These proteins interact with multiple partners and are regulated by various stimuli. They associate with small GTPase Cdc42 and the cytoskeletal organizing complex Arp2/3, both key regulators of actin filament formation.
Wiskott-Aldrich syndrome is a rare, inherited, X-linked recessive disease characterized by immune dysregulation and microthrombocytopenia, caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein expressed exclusively in hematopoietic cells, which exhibit signaling and cytoskeletal abnormalities in affected patients. A transcript variant with an alternative promoter and different 5' UTR sequence has also been described, though its full-length nature remains unclear.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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