Thermo Fisher Scientific PARN Monoclonal Antibody (OTI4D6), TrueMAB
Human PARN 단백질을 표적으로 하는 Mouse monoclonal antibody로 Western blot에 적합합니다. TrueMAB 형식으로 높은 특이성과 재현성을 제공합니다. 액상 형태로 1 mg/mL 농도이며, -20°C에서 보관합니다.
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- TA802569
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human PARN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a 3'-exoribonuclease, similar to the RNase D family of 3'-exonucleases. It prefers poly(A) as substrate and efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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