Thermo Fisher Scientific L2HGDH Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human L2HGDH(Accession Q9H9P8), corresponding to amino acid residues P276-G326. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:L2HGDH,uniProtId:Q9H9P8-1,ncbiNodeId:9606,antigenRange:276-326,antigenLength:463,antigenImageFileName:PA5-104318_L2HGDH_Q9H9P8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-104318_L2HGDH_Q9H9P8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2853628

Product Specific Information

Antibody detects endogenous levels of total L2HGDH.

Target Information

This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.