Thermo Fisher Scientific Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody (TGB04, TGB05)
Thyroglobulin 단백질을 표적하는 인간, 마우스, 랫트 반응성 단일클론 항체. IHC 및 Flow Cytometry에 적합하며, Protein A/G 정제된 액상 형태. 갑상선 세포 마커로 연구용에 최적화.
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- 7038-MSM4-P1ABX
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.1–0.2 µg/mL |
| Flow Cytometry (Flow) | 0.5–1.0 µg/10^6 cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TGB04, TGB05 |
| Immunogen | Human thyroid follicular cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3. Thyroid disorders are largely autoimmune in origin, and anti-thyroglobulin autoantibodies were the first such factors discovered. Anti-hTG is detected in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves disease), with the highest levels in Hashimoto thyroiditis. It is also characteristic of thyroid cancer and can be used for monitoring cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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