Thermo Fisher Scientific Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody (TGB24)
인체 Thyroglobulin을 표적으로 하는 단클론 항체로, 갑상선 세포 마커 연구에 적합. IHC 및 ELISA 적용 가능. 단클론 Mouse IgG1 형식이며, Protein A/G로 정제된 액상 형태. 연구용으로만 사용.
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Thermo Fisher Scientific Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody (TGB24)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TGB24 |
| Immunogen | Human thyroid follicular cells (Thyroglobulin, UniProt ID: P01266-1, antigen length: 2768 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a key role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones (T4 and T3).
Thyroid disorders often have autoimmune origins, and anti-thyroglobulin autoantibodies were the first discovered markers. Anti-hTG is found in all thyroid autoimmune diseases, including Hashimoto thyroiditis and Graves disease, with the highest levels observed in Hashimoto thyroiditis. It is also characteristic of thyroid cancer and can be used for patient follow-up.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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