Thermo Fisher Scientific TIMM50 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 190-456 of human TIMM50 (NP_001001563.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TIMM50,uniProtId:Q3ZCQ8-2,ncbiNodeId:9606,antigenRange:190-456,antigenLength:456,antigenImageFileName:PA5-110489_TIMM50_Q3ZCQ8-2_Rabbit.svg,antigenImageFileNamePDP:PA5-110489_TIMM50_Q3ZCQ8-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.83 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855900

Product Specific Information

Immunogen sequence: GNNPVDENGA KIPDEFDNDP ILVQQLRRTY KYFKDYRQMI IEPTSPCLLP DPLQEPYYQP PYTLVLELTG VLLHPEWSLA TGWRFKKRPG IETLFQQLAP LYEIVIFTSE TGMTAFPLID SVDPHGFISY RLFRDATRYM DGHHVKDISC LNRDPARVVV VDCKKEAFRL QPYNGVALRP WDGNSDDRVL LDLSAFLKTI ALNGVEDVRT VLEHYALEDD PLAAFKQRQS RLEQEEQQRL AELSKSNKQN LFLGSLTSRL WPRSKQP

Target Information

TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50) is an enzyme that in humans is encoded by the TIMM50 gene. Tim50 is a subunit of the Tim23 translocase complex in the inner mitochondrial membrane. Mutations in TIMM50 can lead to epilepsy, severe intellectual disability, and 3-methylglutaconic aciduria. TIMM50 expression is increased in breast cancer cells and decreased in hypertrophic hearts.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.