Thermo Fisher Scientific MAGI3 Polyclonal Antibody
Human MAGI3 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 고농도(0.94 mg/mL) 액상 형태로 제공됩니다. 다양한 종에 예측 반응성을 보입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 62–372 of Human MAGI3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2548923 |
Product Specific Information
- Recommended positive controls: IMR32, HeLa
- Predicted reactivity: Mouse (96%), Rat (95%), Chicken (93%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a 130 kDa guanylate kinase belonging to a family of multi-PDZ domain-containing guanylate kinases. These proteins are localized to epithelial cell tight junctions. MAGI3 interacts with PTEN/MMAC to modulate AKT/protein kinase B (PKB) activity, positioning PTEN/MMAC phosphatase at subcellular sites involved in cell proliferation and survival. MAGI3 includes an N-terminal guanylate kinase domain, a WW domain, and five PDZ domains.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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