Thermo Fisher Scientific PARP14 Polyclonal Antibody
Human PARP14 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF 실험에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로 DNA 손상 및 전사 조절 관련 PARP14 기능 분석에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [참고 문헌 없음]
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: [참고 문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PARP14 (Control fragment Product #RP-89868) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2789525 |
Product Specific Information
Immunogen sequence:
RYFLLCHSSL LDHLLTECPE IEICYDRVTQ HLCLKGPSAD VYKAKCEIQE KVYTMAQKNI QVSPEIFQFL QQVNWKEFSK CLFIAQKILA LYELEGTTVL LTSCSSEALL
Target Information
Poly [ADP-ribose] polymerase 14 (PARP14) is a protein belonging to the PARP family, associated with B aggressive lymphoma. Poly ADP ribosylation is a DNA damage–dependent post-translational modification of histones and other nuclear proteins that mediates DNA repair. PARP proteins with a macrodomain are also involved in gene expression through transcriptional regulation.
PARP14 controls STAT6-dependent transcription by enhancing promoter binding in the presence of IL4 stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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