Thermo Fisher Scientific CYSLTR1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CYSLTR1 for WB and ICC/IF applications. Detects endogenous CLTR1. Supplied as liquid form, 1 mg/mL, affinity purified, stored at -20°C in PBS with glycerol. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CYSLTR1 (Accession Q9Y271), corresponding to amino acid residues K139–L189 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851499 |
Product Specific Information
Antibody detects endogenous levels of total CLTR1.
Target Information
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least two receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, edema, eosinophil migration, and damage to the mucus layer in the lung.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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