Thermo Fisher Scientific BAI1 Polyclonal Antibody
BAI1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며 항체는 액상 형태로 제공됩니다. p53 신호 관련 뇌 혈관 형성 억제 연구에 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BAI1 (Accession O14514), corresponding to amino acid residues R699–V749 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815896 |
Product Specific Information
This antibody detects endogenous levels of total BAI1.
Target Information
Adgrb1 (also known as BAI1) is a phosphatidylserine receptor involved in the engulfment of apoptotic cells and acts as a potent inhibitor of angiogenesis in the brain. It may function as a mediator of p53 signaling in glioblastoma suppression, contributing to cell adhesion and signal transduction in neural tissues.
Angiogenesis, the process of new blood vessel formation, is tightly regulated by a balance between stimulators and inhibitors. In tumors, this balance shifts toward angiogenesis promotion, supporting tumor growth and metastasis. Adgrb1 expression is induced by wild-type p53 and may act as a growth suppressor of glioblastomas. It belongs to the secretin receptor family and is associated with diseases such as glioblastoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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