Thermo Fisher Scientific EMR4 Polyclonal Antibody
EMR4 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunocytochemistry에 적합합니다. 인간과 생쥐 시료 모두 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ADGRE4P (Accession Q86SQ3), corresponding to amino acid residues K129–L179 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851503 |
Product Specific Information
Antibody detects endogenous levels of total EMR4.
Target Information
FIRE is a 689 amino acid protein that maps to human gene EMR4. Also known as EGF-like module-containing mucin-like hormone receptor-like 4, it belongs to the G protein-coupled receptor 2 family, LN-TM7 subfamily.
The EGF-TM7 family includes proteins with EGF-like domains at the extracellular N-terminus coupled to a classical seven-transmembrane (TM7) cassette.
FIRE mediates cellular interactions between myeloid cells and beta cells. It is a membrane-bound, multi-pass protein cleaved into two subunits: an extracellular alpha subunit and a seven-transmembrane subunit.
FIRE contains one GPS (G protein-coupled receptor proteolytic cleavage site) domain and two EGF-like domains, the second of which mediates ligand interaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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