Thermo Fisher Scientific NFkB p105 Polyclonal Antibody
NFkB p105 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 다양한 종(인간, 마우스 등)에 반응하며, p50 등 다른 NF-κB 구성요소와 교차 반응하지 않습니다. 항원 친화 크로마토그래피로 정제된 고품질 연구용 항체입니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunoprecipitation (IP) | 1:50 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mink, Mouse, Non-human primate, Pig, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids at the carboxy-terminus of human NFkB1 p105 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 30 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10983940 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with the p50 subunit or other NF-κB family members.
Target Information
NF-κB is a nuclear transcription factor activated by various extracellular and intracellular stimuli such as cytokines, UV radiation, stress, injury, and microbial products. It regulates cellular processes including growth, differentiation, proliferation, apoptosis, and inflammation.
NFKB1 (p50) is a 50 kDa functional subunit of NF-κB and a member of the Rel protein family. It is synthesized as a p105 precursor containing an N-terminal RHD region responsible for nuclear localization, DNA-binding, and dimerization. NFKB1 (p50) forms homodimers or heterodimers with p65 to create functional NF-κB complexes. NF-κB plays roles in various pathological conditions such as AIDS, metastatic cancer, and rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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