Thermo Fisher Scientific F7 Polyclonal Antibody
인간, 마우스, 랫트 시료에서 F7 단백질 검출용 Rabbit Polyclonal 항체. Western blot 및 ELISA에 적합. 정제된 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 240–400 of human F7 (NP_062562.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.86 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855114 |
Product Specific Information
Immunogen sequence:
RNLIAVLGEH DLSEHDGDEQ SRRVAQVIIP STYVPGTTNH DIALLRLHQP VVLTDHVVPL CLPERTFSER TLAFVRFSLV SGWGQLLDRG ATALELMVLN VPRLMTQDCL QQSRKVGDSP NITEYMFCAG YSDGSKDSCK GDSGGPHATH YRGTWYLTGIV
Target Information
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. It circulates in the blood as a zymogen and is activated by factor IXa, Xa, XIIa, or thrombin. Upon activation, it forms a heavy chain (catalytic domain) and a light chain (EGF-like domains) linked by a disulfide bond. In the presence of factor III and calcium ions, activated factor VII initiates the coagulation cascade by converting factor IX to IXa and/or factor X to Xa. Defects in F7 production can cause coagulopathy.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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