
Thermo Fisher Scientific SH3PXD2A Monoclonal Antibody (OTI1H9), TrueMAB
인간 SH3PXD2A 단백질(299-395 aa)에 특이적인 Mouse IgG1 단일클론 항체. Western blot에 1:2,000 희석으로 검증됨. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. -20°C에서 냉동 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 299–395 of human SH3PXD2A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation, and invasiveness of some cancer cells.
Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs), and phosphoinositides.
Acts as an organizer protein allowing NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and localization.
In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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