Thermo Fisher Scientific SH3PXD2A Monoclonal Antibody (OTI4B8), TrueMAB
인간 SH3PXD2A 단백질(aa 299–395)에 특이적인 Mouse IgG2b 단클론 항체로 Western blot에 적합. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol 버퍼에 보존. 세포 침습 및 ROS 생성 연구용으로 활용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 299–395 of human SH3PXD2A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells.
Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides.
Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization.
In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: TA811759_SH3PXD2A_Q5TCZ1-1_House_mouse.svg)
(이미지: TA811759_SH3PXD2A_Q5TCZ1-1_House_mouse_PDP.jpeg)
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