
Thermo Fisher Scientific BFSP2 Monoclonal Antibody (OTI2G2), TrueMAB
BFSP2 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간 시료 반응성이 있으며, carrier-free 형태로 재결정화 및 결합 실험에 활용 가능합니다. 연구용 전용 제품으로 고순도 친화 크로마토그래피 정제.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 184–415 of human BFSP2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
More than 99% of the vertebrate ocular lens consists of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins—phakinin (BFSP2) and filensin—are expressed only after fiber cell differentiation begins. Both proteins form a unique cytoskeletal structure called the beaded filament (BF).
Mutations in the BFSP2 gene are associated with juvenile-onset progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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