Thermo Fisher Scientific GDNF Polyclonal Antibody
인간 GDNF 단백질을 인식하는 염소 유래 다클론 항체로, 신경영양 인자 연구에 적합합니다. 뉴트럴라이제이션 및 억제 분석에 사용 가능하며, 단백질 G 정제 및 PBS 버퍼에 보존되어 있습니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific GDNF Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Neutralization (Neu) | 2.6 µg/mL |
| Inhibition Assays (IA) | 2.6 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length human GDNF protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_794354 |
Product Specific Information
- Neutralization: ND50 = 2.6 µg/mL
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
GDNF (Glial cell line-derived neurotrophic factor) is a glycosylated, disulfide-bonded homodimer molecule.
It was first discovered as a potent survival factor for midbrain dopaminergic neurons and shown to rescue these neurons in animal models of Parkinson’s disease.
GDNF is approximately 100 times more efficient as a survival factor for spinal motor neurons compared to neurotrophins.
It enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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