Thermo Fisher Scientific OSR1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (IHC)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:2,000

-

Immunoprecipitation (IP)

2-5 µg/mg lysate

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 325 and 375 of human oxidative-stress responsive 1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OXSR1,uniProtId:O95747-1,ncbiNodeId:9606,antigenRange:325-375,antigenLength:527,antigenImageFileName:A301-578A_OXSR1_O95747-1_Rabbit.svg,antigenImageFileNamePDP:A301-578A_OXSR1_O95747-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

tris citrate/phosphate, pH 7-8

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Target Information

OXSR1 serine/threonine kinase or (OSR1) is activated by osmotic stresses and regulates downstream protein kinases such as PAK1 in order to establish the sensor/signaling modules that initiate the cellular response to environmental stress. OXSR1 can be phosphorylated by ATM or ATR during the DNA damage process. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.