Thermo Fisher Scientific CIDEA Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MRGDRASGGP GNHNGSWARE GPRLGPSWKR GLWSPRGGPN RPAEPSRPLT FMGSQTKRVL FTPLMHPARP FRVSNHDRSS RRGVMASSLQ ELISKTLDAL VIATGLVTLV LEEDGTVVDT EEFFQTLGDN THFMILEKGQ KWMPGSQHVP TCSPPKRSGI ARVTFDLYRL NPKDFIGCLN VKATMYEMYS VSYDIRCTGL KGLLRSLLRF LSYSAQVTGQ FLIYLGTYML RVLDDKEERP SLRSQAKGRF TCG

Target Information

This gene encodes the homolog of the mouse protein CIDEA that has been shown to activate apoptosis. This activation is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice lacking functional CIDEA exhibit higher metabolic rates, increased lipolysis in brown adipose tissue, and elevated core body temperatures under cold conditions. They are resistant to diet-induced obesity and diabetes, suggesting a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: H00001149-D01P_CIDEA_O60543-1_Rabbit.svg, H00001149-D01P_CIDEA_O60543-1_Rabbit_PDP.jpeg)