Thermo Fisher Scientific CIDEA Monoclonal Antibody (4B9)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

1 ng/mL

-

Immunoprecipitation (IP)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

4B9

Immunogen

CIDEA (AAH31896, 1 a.a. approximately 253 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CIDEA,uniProtId:O60543-1,ncbiNodeId:9606,antigenRange:1-219,antigenLength:219,antigenImageFileName:H00001149-M01_CIDEA_O60543-1_House_mouse.svg,antigenImageFileNamePDP:H00001149-M01_CIDEA_O60543-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MRGDRASGGP GNHNGSWARE GPRLGPSWKR GLWSPRGGPN RPAEPSRPLT FMGSQTKRVL FTPLMHPARP FRVSNHDRSS RRGVMASSLQ ELISKTLDAL VIATGLVTLV LEEDGTVVDT EEFFQTLGDN THFMILEKGQ KWMPGSQHVP TCSPPKRSGI ARVTFDLYRL NPKDFIGCLN VKATMYEMYS VSYDIRCTGL KGLLRSLLRF LSYSAQVTGQ FLIYLGTYML RVLDDKEERP SLRSQAKGRF TCG

Target Information

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.