Thermo Fisher Scientific CDH6 Polyclonal Antibody, MaxPab

Applications

Western Blot (WB)

• Tested Dilution: 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MRTYRYFLLL FWVGQPYPTL STPLSKRTSG FPAKKRALEL SGNSKNELNR SKRSWMWNQF FLLEEYTGSD YQYVGKLHSD QDRGDGSLKY ILSGDGAGDL FIINENTGDI QATKRLDREE KPVYILRAQA INRRTGRPVE PESEFIIKIH DINDNEPIFT KEVYTATVPE MSDVGTFVVQ VTATDADDPT YGNSAKVVYS ILQGQPYFSV ESETGIIKTA LLNMDRENRE QYQVVIQAKD MGGQMGGLSG TTTVNITLTD VNDNPPRFPQ STYQFKTPES SPPGTPIGRI KASDADVGEN AEIEYSITDG EGLDMFDVIT DQETQEGIIT VKKLLDFEKK KVYTLKVEAS NPYVEPRFLY LGPFKDSATV RIVVEDVDEP PVFSKLAYIL QIREDAQINT TIGSVTAQDP DAARNPVKYS VDRHTDMDRI FNIDSGNGSI FTSKLLDRET LLWHNITVIA TEINNPKQSS RVPLYIKVLD VNDNAPEFAE FYETFVCEKA KADQLIQTLH AVDKDDPYSG HQFSFSLAPE AASGSNFTIQ DNKDNTAGIL TRKNGYNRHE MSTYLLPVVI SDNDYPVQSS TGTVTVRVCA CDHHGNMQSC HAEALIHPTG LSTGALVAIL LCIVILLGKL VLPASYLPMV RGSHCYCDTL DLSASPIKAY SLI

Target Information

Cadherins constitute a family of transmembrane glycoproteins involved in Ca²⁺-dependent cell-cell interactions. Members of this family are differentially expressed in various tissues and function in the maintenance of tissue integrity and morphogenesis.

Cadherins are divided into:

• Type I cadherins: E-cadherin (cadherin-1), N-cadherin (cadherin-2), P-cadherin (cadherin-3), R-cadherin (cadherin-4)
• Type II cadherins: K-cadherin (cadherin-6), OB-cadherin (cadherin-11)

Cadherin-6 is expressed in the proximal tubule epithelium of the kidney, from which most renal cell carcinomas are derived.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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