Thermo Fisher Scientific CDH6 Monoclonal Antibody (2F2)
인간 CDH6(K-cadherin)을 인식하는 Mouse IgG1 단클론 항체로 Western blot 및 ELISA에 적합. GST 태그가 포함된 재조합 단백질로 면역원 제작. PBS(pH 7.4) 용액 형태, 보존제 없음. -20°C 보관, 동결-해동 반복 피할 것.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F2 |
| Immunogen | CDH6 (NP_004923, 513–612 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
DKDDPYSGHQ FSFSLAPEAA SGSNFTIQDN KDNTAGILTR KNGYNRHEMS TYLLPVVISD NDYPVQSSTG TVTVRVCACD HHGNMQSCHA EALIHPTGLS
Target Information
Cadherins constitute a family of transmembrane glycoproteins involved in Ca²⁺-dependent cell-cell interactions.
Members of this family are differentially expressed in various tissues and function in maintaining tissue integrity and morphogenesis.
Cadherins are divided into:
- Type I cadherins: E-cadherin (cadherin-1), N-cadherin (cadherin-2), P-cadherin (cadherin-3), R-cadherin (cadherin-4)
- Type II cadherins: K-cadherin (cadherin-6), OB-cadherin (cadherin-11)
Cadherin-6 is expressed in the proximal tubule epithelium of the kidney, from which most renal cell carcinomas are derived.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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