Thermo Fisher Scientific Leptin Polyclonal Antibody
Leptin 단백질을 인식하는 Rabbit Polyclonal Antibody로서 Human, Mouse, Rat에 반응합니다. Western Blot, IHC, ICC/IF, ELISA 등에 사용 가능하며, Protein A로 정제된 액상 형태입니다. 체중 조절 및 대사 연구용으로 적합합니다.
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Thermo Fisher Scientific Leptin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Leptin, amino acids 101–167 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Leptin is a 167 amino acid protein hormone that regulates body weight, metabolism, and reproductive function. It is approximately 16 kDa and encoded by the obese (ob) gene. Leptin is mainly secreted by adipocytes and also by stomach epithelium and placenta cells. Its receptors are highly expressed in the hypothalamus, T lymphocytes, and vascular endothelial cells. Leptin influences food intake, energy expenditure, adiposity, hematopoiesis, angiogenesis, wound healing, inflammation, immune responses, pubertal development, and fetal growth. It plays roles in obesity, anorexia nervosa, insulin resistance, and hypertension, and regulates fatty acid oxidation enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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