Thermo Fisher Scientific DNM2 Monoclonal Antibody (6C9)
DNM2 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot 및 ELISA에 적합. 인간 시료 반응성, GST 태그 결합 재조합 단백질을 면역원으로 사용. 액상 형태, PBS 버퍼, 보존제 없음, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C9 |
| Immunogen | DNM2 (AAH54501, 611–710 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SWKASFLRAG VYPEKDQAEN EDGAQENTFS MDPQLERQVE TIRNLVDSYV AIINKSIRDL MPKTIMHLMI NNTKAFIHHE LLAYLYSSAD QSSLMEESAD
Target Information
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules and are implicated in processes such as endocytosis, cell motility, and membrane remodeling during activities like bone resorption by osteoclasts. They bind actin and other cytoskeletal proteins and can self-assemble, stimulating GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described; additional variants may exist but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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