Thermo Fisher Scientific p400 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:5,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Horse, Guinea pig, Pig, Orangutan, Monkey, Gorilla, and Chimpanzee.

Target Information

Component of the NuA4 histone acetyltransferase complex, involved in transcriptional activation of select genes by acetylation of nucleosomal histones H4 and H2A. This modification may alter nucleosome–DNA interactions and promote binding of modified histones with transcriptional regulators. EP400 may be required for activation of E2F1 and MYC target genes during cellular proliferation, and may regulate ZNF42 transcription activity.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.