Thermo Fisher Scientific METTL7B Polyclonal Antibody
METTL7B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, ICC/IF, ELISA에 적합합니다. Human, Mouse, Rat 반응성을 가지며, 고순도 Affinity Chromatography 정제 및 안정적인 PBS/glycerol 저장 buffer를 사용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 165–244 of human METTL7B (NP_689850.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.544 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914647 |
Product Specific Information
- Positive test controls include: HT-29, Mouse liver, Rat liver
- Immunogen sequence:
RPGGVLFFWE HVAEPYGSWA FMWQQVFEPT WKHIGDGCCL TRETWKDLEN AQFSEIQMER QPPPLKWLPV GPHIMGKAVK
Target Information
MettL7B belongs to the methyltransferase superfamily and is a probable methyltransferase. Methyltransferases transfer methyl groups to nucleic bases in DNA or amino acids in proteins, influencing gene regulation without altering DNA sequences. DNA methylation plays a crucial role in mammalian embryonic development and gene expression control. Aberrant methylation of tumor suppressor genes is associated with cancer progression and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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