Thermo Fisher Scientific ILK Monoclonal Antibody (OTI2H3), TrueMAB
Human ILK 단백질을 인식하는 Mouse 단일클론 항체로 Western blot에 최적화됨. Affinity chromatography로 정제된 액상 형태이며 PBS/BSA/glycerol buffer에 보관. 세포 내 integrin 신호전달 연구에 활용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H3 |
| Immunogen | Human recombinant protein fragment (aa 1–244 of ILK) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, requiring interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with four ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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