Thermo Fisher Scientific LGR5 Monoclonal Antibody (OTI7F2), TrueMAB
LGR5 단백질을 표적하는 마우스 단클론 항체로, Flow Cytometry에 적합합니다. Human, Mouse, Rat에 반응하며, 동결건조 형태로 제공됩니다. PBS 버퍼 기반으로 보존제가 없으며, 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–543 of human LGR5 produced in HEK293 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain approximately 1 mg/mL antibody concentration.
For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
G protein-coupled receptor GPR49 (LGR5) is expressed in brain, skeletal muscle, placenta, and spinal cord.
It belongs to the GPCR family, characterized by seven membrane-spanning helices and existing in active and inactive forms.
GPCRs are key signaling molecules involved in a wide range of physiological processes and are major targets in pharmacological research.
Examples of GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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