Thermo Fisher Scientific HGF Monoclonal Antibody (OTI1C6), TrueMAB
Human HGF 단백질을 타겟으로 하는 Mouse Monoclonal Antibody (Clone OTI1C6). Western blot에 최적화된 TrueMAB 포맷으로 제공. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, 안정적인 PBS/BSA/glycerol 저장 버퍼 구성.
- 카탈로그번호
- TA807185
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 200–494 of human HGF produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Hepatocyte growth factor (HGF) regulates cell growth, motility, and morphogenesis through activation of a tyrosine kinase signaling cascade upon binding to the proto-oncogenic c-Met receptor. It is secreted by mesenchymal cells and acts as a multifunctional cytokine on epithelial cells. HGF stimulates mitogenesis, cell motility, and matrix invasion, playing a key role in angiogenesis, tumorogenesis, and tissue regeneration.
The inactive single-chain precursor is cleaved by serine proteases into a 69-kDa alpha chain and a 34-kDa beta chain, linked by a disulfide bond to form the active heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but lacks detectable protease activity. Alternative splicing generates multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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