
Thermo Fisher Scientific Diazepam Binding Inhibitor (DBI) Monoclonal Antibody (OTI4A8)
Human DBI 단백질(aa 2-104)에 특이적인 Mouse IgG1 단클론 항체. Western blot에 최적화되어 있으며, carrier-free 형태로 재결합 및 결합 실험에 적합. PBS와 trehalose 기반의 안정적 저장용액 제공.
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Thermo Fisher Scientific Diazepam Binding Inhibitor (DBI) Monoclonal Antibody (OTI4A8)
Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A8 |
| Immunogen | Human recombinant protein fragment (aa 2–104 of human DBI, NP_065438) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Diazepam binding inhibitor (DBI) is a hormone-regulated protein involved in lipid metabolism and modulation of signal transduction at GABA-A receptors in brain synapses.
It is conserved from yeast to mammals, with a highly conserved hydrophobic domain that binds medium- and long-chain acyl-CoA esters.
DBI also participates in feedback regulation of pancreatic secretion, postprandial release of cholecystokinin, and corticotropin-dependent adrenal steroidogenesis.
Three pseudogenes have been identified on chromosomes 6, 8, and 16, and multiple transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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