Thermo Fisher Scientific Hexokinase 2 Polyclonal Antibody
Hexokinase 2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. Protein A 정제, 1 mg/mL 농도, 연구용으로 적합.
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Thermo Fisher Scientific Hexokinase 2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:300–1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Immunocytochemistry (ICC/IF): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Hexokinase II/HxK2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In vertebrates, there are four major glucose-phosphorylating isoenzymes: hexokinase I, II, III, and IV. Hexokinase catalyzes the first step of glucose metabolism by phosphorylating glucose to glucose-6-phosphate, committing it to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by glucose-6-phosphate. Hexokinase 2 is predominantly expressed in insulin-responsive tissues such as skeletal muscle. Its expression is insulin-regulated and is associated with enhanced glycolysis observed in rapidly growing cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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