Thermo Fisher Scientific CHD1L Recombinant Rabbit Monoclonal Antibody (JG35-44)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

Flow Cytometry (Flow)

1:50-1:100

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

JG35-44

Immunogen

Recombinant protein within Human CHD1L aa 680-820 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHD1L,uniProtId:Q86WJ1-1,ncbiNodeId:9606,antigenRange:680-820,antigenLength:897,antigenImageFileName:MA5-34732_CHD1L_Q86WJ1-1_Rabbit.svg,antigenImageFileNamePDP:MA5-34732_CHD1L_Q86WJ1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Shipping conditions

Wet ice

RRID

AB_2848640

Product Specific Information

Positive Control: HepG2, human tonsil tissue, human colon cancer tissue, mouse testis tissue, HepG2.

Target Information

In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.