Thermo Fisher Scientific HYAL2 Polyclonal Antibody
HYAL2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 사용 가능. Human, Mouse, Rat에 반응하며, Affinity chromatography로 정제됨. PBS/50% glycerol 저장, -20°C 보관.
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- PA5115387
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HYAL2 (Accession Q12891), corresponding to amino acid residues G204–L254 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900023 |
Product Specific Information
Antibody detects endogenous levels of total HYAL2.
Target Information
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and its fragments are involved in cell proliferation, migration, and differentiation. Although previously thought to be a lysosomal enzyme active below pH 4, the encoded protein is likely a GPI-anchored cell surface protein. It also serves as a receptor for the oncogenic Jaagsiekte sheep retrovirus. The gene is located in a chromosome 3p21.3 region associated with tumor suppression and encodes two alternatively spliced transcript variants differing in the 5' UTR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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