Thermo Fisher Scientific SMAD7 Polyclonal Antibody
SMAD7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며 인간, 마우스, 양에 반응. 단백질 G 정제, 1.0 mg/mL 농도, PBS 용액 형태로 제공. 연구용 전용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 4–6 µg/mL | View 6 publications |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Sheep |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Two peptides made from within amino acids 10–50 of human SMAD7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2193487 |
Product Specific Information
This antibody is predicted to react with chimpanzee, canine, pufferfish, xenopus, and zebrafish based on sequence homology.
Suggested positive control: A549, HepG2.
Target Information
SMADs are members of the MAD-related family of molecules. These intracellular proteins are essential components of the signaling pathways of serine/threonine kinase receptors belonging to the transforming growth factor beta (TGF-β) superfamily.
SMADs are classified as:
- Receptor-regulated SMADs (R-SMADs): SMAD1, SMAD2, SMAD5, SMAD8, SMAD9
- Common-mediator SMAD (Co-SMAD): SMAD4
- Inhibitory SMADs (I-SMADs): SMAD6, SMAD7
SMAD1, SMAD5, SMAD8, and SMAD9 share high sequence homology. Antibodies recognizing common sequences among these proteins are available. SMAD8 and SMAD9 are often used interchangeably in literature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA1-41506_SMAD7_O15105-1_Rabbit.svg, PA1-41506_SMAD7_O15105-1_Rabbit_PDP.jpeg)
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