Thermo Fisher Scientific Smallpox Virus B5R Polyclonal Antibody
Rabbit polyclonal antibody recognizing smallpox virus B5R protein. Suitable for Western blot applications. Predicted cross-reactivity with camel, bovine, monkey, and rabbit. Supplied as liquid, 0.5 mg/mL in PBS with gelatin and sodium azide. For resear...
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Applications
- Western Blot (WB): 0.1–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues I(33) Q E Y N L I R T Y K K V D K(47) of smallpox B5R |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1087346 |
Product Specific Information
This antibody is predicted to react with camel, bovine, monkey, and rabbit samples based on sequence homology.
Target Information
B5R is an extracellular enveloped virus (EEV)-specific Type I membrane glycoprotein essential for EEV formation. Vaccinia virus, a member of the Poxviridae family, is a dsDNA enveloped virus with four virion stages, among which EEV is critical for cell-to-cell and long-range viral infection. Some cellular antigens are associated with EEV and vary with the cell type used to grow the virus.
B5R contains a large ectodomain with regions similar to SCR domains of complement regulatory proteins, followed by a transmembrane region and a cytoplasmic tail. It is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, and EEV formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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