
Thermo Fisher Scientific HMGA1 Polyclonal Antibody
HMGA1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(Paraffin)에 적합합니다. 인간, 닭, 소 시료에 반응이 예측되며, 세포 내 전사 조절 및 암 전이 연구에 유용합니다. 4°C 단기, -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 19–32 of human HMGA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2264019 |
Product Specific Information
This antibody is predicted to react with chicken and bovine samples based on sequence homology.
Suggested positive control: human pancreas protein, antigen standard for HMGA1 (transient overexpression lysate), pancreas lysate.
Target Information
HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells.
The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins.
The encoded protein is frequently acetylated and is found in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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