Thermo Fisher Scientific ULK2 Monoclonal Antibody (5E4)
ULK2 단백질을 인식하는 Mouse monoclonal antibody (Clone 5E4). Western blot과 ELISA에 적합. ULK2의 자가포식 관련 신호전달 연구에 활용 가능. PBS buffer, no preservative, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5E4 |
| Immunogen | ULK2 (AAH34988, 743–843 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
FLRTRTTSVG PSNSGGSLCA MSGRVCVGSP PGPGFGSSPP GAEAAPSLRY VPYGASPPSL EGLITFEAPE LPEETLMERE HTDTLRHLNV MLMFTECVLD L
Target Information
ULK2 (also known as ATG1B) is a key serine/threonine protein kinase acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. ULK2 is also thought to be involved in early neuronal growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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