
Thermo Fisher Scientific ATF2 Monoclonal Antibody (3A3)
ATF2 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot, ELISA, in situ PLA에 적합합니다. 인간 시료 반응성이 있으며, PBS buffer에 보존된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1–5 µg/mL |
| in situ PLA (PLA) | 1:1200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A3 |
| Immunogen | Full-length recombinant ATF2 (NP_001871, 91–190 a.a.) with GST tag (MW 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PFENEFKKAS EDDIKKMPLD LSPLATPIIR SKIEEPSVVE TTHQDSPLPH PESTTSDEKE VPLAQTAQPT SAIVRPASLQ VPNVLLTSSD SSVIIQQAVP *
Target Information
ATF-2 (also known as CRE-BP1) is a transcription factor that binds to AP-1 and CRE DNA response elements and belongs to the ATF/CREB family of leucine zipper proteins. It interacts with viral oncoproteins and cellular tumor suppressors and is a target of SAPK/JNK and p38 MAP kinase signaling pathways. Various cellular stresses such as genotoxic agents, inflammatory cytokines, and UV irradiation activate ATF-2 via phosphorylation at Thr69 and Thr71.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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