Thermo Fisher Scientific PPBP Polyclonal Antibody
Thermo Fisher Scientific의 PPBP Polyclonal Antibody는 인간 PPBP 단백질을 검출하기 위한 토끼 유래 IgG 항체입니다. Western blot 및 IHC(P)에서 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관하며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide of human PPBP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636702 |
Product Specific Information
This antibody detects endogenous levels of total PPBP protein.
Target Information
Members of the α-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines share a conserved motif (Cys-X-Cys) and are chemotactic for neutrophils. The platelet basic protein (PBP), part of this family, is stored in platelet α-granules and released upon activation. Proteolytic cleavage of PBP generates several peptides, including mature PBP, connective tissue-activating peptide III (CTAP III or low affinity platelet factor IV, LA-PF4), β-thromboglobulin (β-TG), and neutrophil-activating peptide 2 (NAP-2). These molecules are involved in inflammation and wound healing, with NAP-2 specifically mediating neutrophil chemotaxis and degranulation. The human PBP gene is located on chromosome 4q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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