Thermo Fisher Scientific SOD3 Polyclonal Antibody
인간 SOD3에 반응하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로 Western blot 및 IHC(Paraffin) 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 0.04–0.4 µg/mL
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SOD3. Recombinant protein control fragment (Product #RP-102921) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647739 |
Product Specific Information
Immunogen sequence:
WTGEDSAEPN SDSAEWIRDM YAKVTEIWQE VMQRRDDDGT LHAACQVQPS ATLDAAQPRV TGVVLFRQLA PRAKLDAFFA LEGFPTEPNS SSRAIHVHQF G
Highest antigen sequence identity to the following orthologs:
- Mouse: 53%
- Rat: 50%
Target Information
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and shows increased expression in actively dividing cells such as testis, thymus, fetal liver, and carcinomas. The protein localizes to the nucleus and promotes the stability and nuclear accumulation of transcriptionally active p53. It phosphorylates Thr18 of p53, reducing its ubiquitination, and may regulate cell proliferation. Additionally, it phosphorylates histone, casein, and transcription factors ATF2 and c-JUN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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