Thermo Fisher Scientific EDC3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human EDC3 protein. Validated for Western blot and ELISA. Suitable for detecting EDC3 in human, mouse, and rat samples. Supplied in PBS with 50% glycerol for stable storage at -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 159–508 of human EDC3 (NP_079359.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.23 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805560 |
Product Specific Information
Immunogen sequence:
HNSWSSSSRH PNQATPKKSG LKNGQMKNKD DECFGDDIEE IPDTDFDFEG NLALFDKAAV FEEIDTYERR SGTRSRGIPN ERPTRYRHDE NILESEPIVY RRIIVPHNVS KEFCTDSGLV VPSISYELHK KLLSVAEKHG LTLERRLEMT GVCASQMALT LLGGPNRLNP KNVHQRPTVA LLCGPHVKGA QGISCGRHLA NHDVQVILFL PNFVKMLESI TNELSLFSKT QGQQVSSLKD LPTSPVDLVI NCLDCPENVF LRDQPWYKAA VAWANQNRAP VLSIDPPVHE VEQGIDAKWS LALGLPLPLG EHAGRIYLCD IGIPQQVFQE VGINYHSPFG CKFVIPLHSA
Positive Samples: U-87MG, MCF-7, HeLa, Mouse pancreas
Cellular Location: Cytoplasm, P-body
Target Information
This gene encodes a protein important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5′ to 3′ mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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