Thermo Fisher Scientific EDC3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 159-508 of human EDC3 (NP_0793592) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EDC3,uniProtId:Q96F86-1,ncbiNodeId:9606,antigenRange:159-508,antigenLength:508,antigenImageFileName:PA5-89418_EDC3_Q96F86-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89418_EDC3_Q96F86-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.23 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805560

Product Specific Information

Immunogen sequence: HNSWSSSSRH PNQATPKKSG LKNGQMKNKD DECFGDDIEE IPDTDFDFEG NLALFDKAAV FEEIDTYERR SGTRSRGIPN ERPTRYRHDE NILESEPIVY RRIIVPHNVS KEFCTDSGLV VPSISYELHK KLLSVAEKHG LTLERRLEMT GVCASQMALT LLGGPNRLNP KNVHQRPTVA LLCGPHVKGA QGISCGRHLA NHDVQVILFL PNFVKMLESI TNELSLFSKT QGQQVSSLKD LPTSPVDLVI NCLDCPENVF LRDQPWYKAA VAWANQNRAP VLSIDPPVHE VEQGIDAKWS LALGLPLPLG EHAGRIYLCD IGIPQQVFQE VGINYHSPFG CKFVIPLHSA; Positive Samples: U-87MG, MCF-7, HeLa, Mouse pancreas; Cellular Location: Cytoplasm, P-body

Target Information

This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5to 3 mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.