Thermo Fisher Scientific Phospho-MYPT1 (Ser507) Polyclonal Antibody
Phospho-MYPT1 (Ser507) 폴리클로날 항체로, 인간 MYPT1 인산화 부위(Ser507)에서 유래한 펩타이드로 제작됨. Western blot에 적합하며, 토끼 IgG 기반 액상 항체. -20°C 보관, 연구용 전용 제품.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-MYPT1 (Ser507) Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MYPT1 around the phosphorylation site of Ser507 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903263 |
Target Information
Myosin phosphatase target subunit 1 (MYPT1), also known as the myosin-binding subunit of myosin phosphatase, is a regulatory component of myosin phosphatase that modulates actin–myosin interactions downstream of Rho GTPase signaling.
RhoA in its active, GTP-bound form interacts with MYPT1 to regulate myosin light chain (MLC) phosphorylation, influencing smooth muscle contraction and cytoskeletal dynamics in nonmuscle cells.
Rho-associated kinase (Rho-kinase) phosphorylates and inactivates MYPT1, reducing phosphatase activity. Overexpression or activation of RhoA increases phosphorylation of both MYPT1 and MLC.
Multiple transcript variants encoding different isoforms of MYPT1 have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.