Thermo Fisher Scientific GABBR2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.6 µg/mL

-

Immunocytochemistry (ICC/IF)

Assay-Dependent

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide (coupled with THG) derived from the last 23 aa of mouse GABA B receptor 2. 100% homology with human GB2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GABBR2,uniProtId:Q80T41-1,ncbiNodeId:10090,antigenRange:23,antigenLength:940,antigenImageFileName:PA1-10032_GABBR2_Q80T41-1_Rabbit.svg,antigenImageFileNamePDP:PA1-10032_GABBR2_Q80T41-1_Rabbit_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

4° C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11153236

Product Specific Information

This antibody recognizes the C-terminus of gamma-aminobutyric acid (GABA) B receptor 2 (epitope: the last 23 aa).

Target Information

The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.