Thermo Fisher Scientific GABBR2 Polyclonal Antibody
GABBR2 단백질의 C-말단을 인식하는 Rabbit Polyclonal 항체. Western blot 및 ICC/IF에 사용 가능. 인간, 생쥐 GABA B receptor 2에 높은 상동성. 액상 형태로 4°C 보관, 연구용 전용 시약.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.6 µg/mL | - |
| Immunocytochemistry (ICC/IF) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (coupled with THG) derived from the last 23 amino acids of mouse GABA B receptor 2. 100% homology with human GB2. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153236 |
Product Specific Information
This antibody recognizes the C-terminus of gamma-aminobutyric acid (GABA) B receptor 2 (epitope: the last 23 amino acids).
Target Information
The multi-pass membrane protein GABBR2 belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily.
GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems that regulate neurotransmitter release, ion channel activity, and adenylyl cyclase.
This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective alone.
Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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