Thermo Fisher Scientific Cytochrome C Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:10,000

-

ELISA (ELISA)

1:2,000-1:10,000

-

Product Specifications

Species Reactivity

Bovine, Human, Mouse, Rat

Host/Isotype

Chicken / IgY

Class

Polyclonal

Type

Antibody

Immunogen

Purified bovine cytochrome c protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cytochrome C,uniProtId:P62894-1,ncbiNodeId:9913,antigenRange:1-105,antigenLength:105,antigenImageFileName:PA1-9585_Cytochrome_C_P62894-1_Chicken.svg,antigenImageFileNamePDP:PA1-9585_Cytochrome_C_P62894-1_Chicken_PDP.jpeg,sortOrder:4}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2277131

Product Specific Information

PA1-9585 detects Cytochrome C in human, mouse, bovine and rat samples.

PA1-9585 has been successfully used in Western blot and ELISA procedures. By Western blot, PA1-9585 detects a 12 kDa protein representing Cytochrome C.

PA1-9585 immunogen is a purified bovine cytochrome c protein

Target Information

Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.