Thermo Fisher Scientific MMP17 Polyclonal Antibody
Human, Mouse, Rat 반응성의 MMP17 폴리클로날 항체로 Western Blot, IHC, ELISA에 사용 가능. Recombinant fusion protein을 면역원으로 제작. 고순도 Affinity chromatography 정제 및 PBS/glycerol buffer로 안정적 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific MMP17 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 265–565 of human MMP17 (NP_0572394) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901610 |
Product Specific Information
- Positive Samples: SW480, RAW264.7, Mouse testis, Rat testis
- Immunogen sequence:
IMRPYYQGPV GDPLRYGLPY EDKVRVWQLY GVRESVSPTA QPEEPPLLPE PPDNRSSAPP RKDVPHRCST HFDAVAQIRG EAFFFKGKYF WRLTRDRHLV SLQPAQMHRF WRGLPLHLDS VDAVYERTSD HKIVFFKGDR YWVFKDNNVE EGYPRPVSDF SLPPGGIDAA FSWAHNDRTY FFKDQLYWRY DDHTRHMDPG YPAQSPLWRG VPSTLDDAMR WSDGASYFFR GQEYWKVLDG ELEVAPGYPQ STARDWLVCG DSQADGSVAA GVDAAEGPRA PPGQHDQSRS EDGYEVCSCT S
Target Information
Matrix metalloproteinase (MMP) family proteins are involved in extracellular matrix breakdown during normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in pathological processes like arthritis and metastasis.
Most MMPs are secreted as inactive proproteins activated by extracellular proteinases.
This gene encodes a member of the membrane-type MMP (MT-MMP) subfamily, unique for being GPI-anchored rather than transmembrane. The protein activates MMP-2 by cleavage.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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