Thermo Fisher Scientific Growth Hormone Polyclonal Antibody, Biotin
Biotin 결합형 성장호르몬 폴리클로날 항체로 Western blot, IHC, ICC, ELISA 등 다양한 응용 가능. 사람, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제. 연구용 성장호르몬 검출 및 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | N-epitope synthetic peptide within amino acid region 1–60 on human Growth Hormone beta subunit protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones that play an important role in growth control. The GH1 gene, along with four related genes, is located at the growth hormone locus on chromosome 17. These genes share a high degree of sequence identity, and alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.
hGH is produced by somatotroph cells in the pituitary and acts through cytokine receptor subfamily membrane receptors. Its major role in stimulating body growth involves stimulating the liver and other tissues to secrete IGF-1. It promotes myoblast differentiation and proliferation, amino acid uptake, and protein synthesis in muscle and other tissues. Mutations or deletions in the GH1 gene can cause growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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