Thermo Fisher Scientific Pozelimab Recombinant Human Monoclonal Antibody

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Human / IgG4, kappa

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Immunogen

Human C5

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.36 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.5

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911378

Product Specific Information

Endotoxin level < 0.01EU/µg by LAL method

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Target Information

Pozelimab is an investigational fully human monoclonal antibody, invented using Regeneron`s proprietary VelocImmune technology, which aims to block the complement signaling pathway by binding to complement factor C5. It also prevents the destruction of red blood cells (hemolysis) that causes paroxysmal nocturnal hemoglobinuria and other disease symptoms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.