Thermo Fisher Scientific AP2M1 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal Antibody로, AP2M1 단백질 검출에 사용. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 고순도(>95%)이며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in Human AP2M1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803516 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
The heterotetrameric coat assembly protein complex, known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family.
The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase responsible for proton pumping in the acidification of endosomes and lysosomes.
AP2M1 has been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use the AP-2 complex to enhance endocytosis of both CD4 and class I MHC.
AP2M1 may also regulate intracellular trafficking and function of CTLA-4 protein. At least two isoforms of AP2M1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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