Thermo Fisher Scientific NFATC2 Polyclonal Antibody
NFATC2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 인간에 반응하고 다른 종에서도 예측 반응성을 가집니다. 액상 형태로 제공되며 안정적인 저장 조건을 갖습니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.3–1 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–6 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QQFRTGLSSPDARYQ) corresponding to the internal amino acids of NFATC2 (aa 729–744) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10988615 |
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse, and rat based on sequence homology.
Tested in Peptide ELISA with an antibody detection limit dilution of 64,000.
Target Information
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of proteins that collectively regulate the immune response.
Four NFAT proteins—NFAT1 (NFATp/NFATc2), NFAT2 (NFATc/NFATc1), NFAT3, and NFAT4 (NFATx/NFATc3)—are encoded on separate genes and expressed as splice variants.
These proteins share limited sequence similarity with the Dorsal/Rel/NFkB family of transcription factors.
NFAT5 differs from isoforms 1–4 by lacking many Fos/Jun contact sites and its localization is not calcineurin-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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