
Thermo Fisher Scientific CD44var (v6) Monoclonal Antibody (VFF-7), Biotin, eBioscience
CD44var (v6) 특이적 단클론 항체로 인간 세포에서 CD44 변이형을 검출. Flow Cytometry에 최적화된 Biotin 결합형 제품. 높은 순도(>95%)와 안정적 보관(2–8°C). 연구용으로만 사용 가능.
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Applications
- Flow Cytometry (Flow): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Biotin, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VFF-7 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 10 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.2–7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 2–8°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10598356 |
Additional Formats
Product Specific Information
Specifically recognizes an epitope encoded by exon v6 on the variant portion of human CD44.
Standard CD44 (CD44s) lacks the entire variable region and is found mainly in cells of lymphohematopoietic origin.
The multiple isoforms (designated CD44v; v = variant) contain alternatively spliced exons inserted within the extracellular domain.
These isoforms are known as CD44v1–CD44v11.
- Applications Tested: Flow Cytometry
- Purity: >95%
Target Information
CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and by some epithelial cells of the intestine and breast.
Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, adhesion, and migration.
It also participates in lymphocyte activation, recirculation, and homing.
CD44 expression may be up-regulated in some carcinomas, potentially related to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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